HCID 22278872, compound → HCID 10236021, compound

Participants

Reaction Steps

A mixture of 20% Pd(OH)2 on carbon (0.3 g) and 1-benzyl-4-dimethylamino-3,3-dimethylpiperidine (4.5 g, 6.0 mmol) in methanol (20 ml) was stirred in hydrogen atmosphere (1 atm.) for 48 hr at room temperature. The catalyst was filtered off, washed with methanol and filtrate was concentrated to afford 4-dimethylamino-3,3-dimethylpiperidine. Yield 1.6 g (95%), C9H20N2, m/z 157 (M+1).

Provenance & Evidence