HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → 1-Carbethoxy-3,5-dimethyl-4-piperidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 1-Benzyl-3,5-dimethylpiperidin-4-one | HCID 22278920 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Carbethoxy-3,5-dimethyl-4-piperidinone | HCID 22278887 | — |
Reaction Steps
Ethyl chloroformate (10.0 g, 90 mmol) was added to a stirred solution of 1-benzyl-3,5-dimethyl-4-piperidinone (5.0 g, 24 mmol) in benzene (20 ml), refluxed with stirring for 6 hr and concentrated to dryness to give 1-carbethoxy-3,5-dimethyl-4-piperidinone as oil. Yield 4.51 g (90%), C10H17NO3, m/z 200 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626032B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-a67fc8f299394bb48ec59e2d46de818c |
| Source note | uspto-grants-2009_12 |