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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865285Generated: October 30, 2026

HCID 69018910, compound → HCID 69017599, compound

https://huagongshe.com/reaction/1865285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69018910HCID 69018910—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 69017599HCID 6901759996.7%

Reaction Conditions

Temperature50 °C

Reaction Steps

cis-4-t-Butyloxycarbonylamino-1-benzyl-3-methylpiperidine (13 g, 0.042 mol) was dissolved in 170 ml methanol and transferred to the Parr pressure reactor after addition of 1.3 g of Pd(OH)2 on carbon. The rqcytoion mixture stirred for 6 hrs at 400 psi pressure at 50° C. Catalyst was removed by filtration and evaporation of the solvent afforded 8.7 g (95%) of titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07626032B2
Source datasetuspto-grants-2009_12
ORD IDord-4de2e2134409407793284dd48f297d26
Source noteuspto-grants-2009_12