HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 24937417, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | Cyclopentanecarbonyl chloride | HCID 78284 | — |
| Reactant | Cyclopentylacetyl chloride | HCID 3485182 | — |
| Reactant | 3,3-Difluorocyclobutane-1-carboxylic acid | HCID 13777789 | — |
| Reactant | HCID 68575668 | HCID 68575668 | — |
| Product | HCID 24937417 | HCID 24937417 | — |
Reaction Steps
The following were prepared analogously from 4,6-dimethyl-5-{5-[2-(3-phenyl-pyrrolidin-3-yl)-ethyl]-hexahydro-pyrrolo[3,4-c]pyrrole-2-carbonyl}-pyridine-2-carbonitrile using the acylating agent in parenthesis in place of 3,3-difluorocyclobutane-carboxylic acid in the final step according to the procedure in step 8 of example 5: III-5 (cyclopentanecarbonyl chloride): III-6 (cyclopentyl-acetyl chloride), III-7 (acetic anhydride) and III-8 (pivaloyl chloride).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625905B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-65cd3327f5674786a4707259e4b1ceda |
| Source note | uspto-grants-2009_12 |