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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865299Generated: October 29, 2026

Sulfuryl chloride → HCID 58782540, compound

https://huagongshe.com/reaction/1865299

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfuryl chlorideHCID 24648—
ReactantBenzonitrile, o-(2-oxazolo(5,4-b)pyridinyl)-HCID 40321—
Reactant3-Fluorobenzenesulfonyl ChlorideHCID 2734258—
ReactantCyclopropanesulfonyl chlorideHCID 2760919—
ReactantCyclopentanesulfonyl chlorideHCID 3717197—
ReactantHCID 68576178HCID 68576178—
ProductHCID 58782540HCID 58782540—

Reaction Steps

The following were prepared analogously from (4,6-dimethyl-pyrimidin-5-yl)-{5-[2-(3-phenyl-azetidin-3-yl)-ethyl]-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl}-methanone using the sulfonyl chloride in parenthesis in place of cyclopentanesulfonyl chloride in the final step: II-2 (m-fluoro-phenylsulfonyl chloride), II-19 (iso-propylsulfonyl chloride) and II-20 (cyclopropyl sulfonyl chloride).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625905B2
Source datasetuspto-grants-2009_12
ORD IDord-3fd06dfb7c394b7fabe1cdd0c8072b97
Source noteuspto-grants-2009_12