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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865303Generated: November 1, 2026

Trifluoroacetic anhydride → HCID 68575830, compound

https://huagongshe.com/reaction/1865303

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic anhydrideHCID 9845—
ReactantPropionyl chlorideHCID 62324—
ReactantIsobutyryl chlorideHCID 62325—
ReactantPivaloyl chlorideHCID 62493—
ReactantIsovaleryl chlorideHCID 66054—
ReactantMethoxyacetyl chlorideHCID 96623—
ReactantCyclopentylacetyl chlorideHCID 3485182—
ReactantHCID 68576499HCID 68576499—
ProductHCID 68575830HCID 68575830—

Reaction Steps

The following were prepared analogously from (4,6-dimethyl-pyrimidin-5-yl)-[5-(3-phenyl-3-piperidin-4-yl-propyl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone using the acylating agent in parenthesis in place of pivaloyl chloride: V-13 (propionyl chloride), V-14 (3-methyl-butyryl chloride), V-19 (isobutyryl chloride), V-16 (methoxyacetyl chloride), V-17 (cyclopentylacetyl chloride) and V-22 (TFAA).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625905B2
Source datasetuspto-grants-2009_12
ORD IDord-53a2f105bed14071bcb396a2d369da65
Source noteuspto-grants-2009_12