alpha-Methyl-DL-serine → HCID 14405755, compound

HRID 1865320Notes

Reaction equation

HRID 1865320 reaction equation
[NH2:1][C:2]([CH3:8])([CH2:6][OH:7])[C:3]([OH:5])=O.[N:9]([C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[C:14]([C:21]([F:24])([F:23])[F:22])[CH:13]=1)=[C:10]=[O:11]>>[OH:7][CH2:6][C:2]1([CH3:8])[NH:1][C:10](=[O:11])[N:9]([C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[C:14]([C:21]([F:22])([F:23])[F:24])[CH:13]=2)[C:3]1=[O:5]

Participants

3

Reactant 2

HCID 94309alpha-Methyl-DL-serineHCID 153425614-Isocyanato-1-nitro-2-(trifluoromethyl)benzene

Product 1

HCID 14405755HCID 14405755, compound

Procedure

Follow the procedure in Example 12, using 2-amino-3-hydroxy-2-methyl-propionic acid and 4-isocyanato-1-nitro-2-trifluoromethyl-benzene, known from the literature as starting material to yield the title compounds as a yellow solid.

Sources & evidence

ORD record
ord-14d886a4e2e346f08db071f6c1e05746
Source dataset
uspto-grants-2009_12
Patent number
US07626036B2

Reaction notes

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