HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Morpholinecarbonyl chloride → 5-[(1,1-Dimethyl)ethyl]-2-[(morpholinocarbonyl)oxy]-N-[3,5-bis(trifluoromethyl)-phenyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Morpholinecarbonyl chloride | HCID 84810 | — |
| Reactant | N-[3,5-Bis(trifluoromethyl)phenyl]-5-[(1,1-dimethyl)ethyl]-2-hydroxybenzamide | HCID 10250695 | — |
| Product | 5-[(1,1-Dimethyl)ethyl]-2-[(morpholinocarbonyl)oxy]-N-[3,5-bis(trifluoromethyl)-phenyl]benzamide | HCID 86604722 | 95% |
Reaction Steps
Using 5-[(1,1-dimethyl)ethyl]-2-hydroxy-N-[3,5-bis(trifluoromethyl)-phenyl]benzamide and morpholine-4-carbonyl chloride as the raw materials, the same operation as the Example 71 gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626042B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-0a6745db9aeb47c5b6ef4054be83d0ef |
| Source note | uspto-grants-2009_12 |