3-Hydroxy-2-naphthoic acid → HCID 13766040, compound

HRID 1865363Notes

Reaction equation

HRID 1865363 reaction equation
[OH:1][C:2]1[C:3]([C:12]([OH:14])=O)=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[F:15][C:16]([F:29])([F:28])[C:17]1[CH:18]=[C:19]([CH:21]=[C:22]([C:24]([F:27])([F:26])[F:25])[CH:23]=1)[NH2:20]>>[OH:1][C:2]1[C:3]([C:12]([NH:20][C:19]2[CH:21]=[C:22]([C:24]([F:25])([F:26])[F:27])[CH:23]=[C:17]([C:16]([F:15])([F:28])[F:29])[CH:18]=2)=[O:14])=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Participants

3

Reactant 2

HCID 71043-Hydroxy-2-naphthoic acidHCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-

Product 1

HCID 13766040HCID 13766040, compoundYield 46.9%

Procedure

Using 3-hydroxynaphthalene-2-carboxylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the Example 1(1) gave the title compound.

Sources & evidence

ORD record
ord-866895469e1541db8d5a86073e92305d
Source dataset
uspto-grants-2009_12
Patent number
US07626042B2

Reaction notes

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