4-Morpholinecarbonyl chloride → HCID 69067799, compound

HRID 1865368Notes

Reaction equation

HRID 1865368 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:22])=[C:6]([CH:21]=1)[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:11]=1[Cl:20])=[O:8].[N:23]1([C:29](Cl)=[O:30])[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:22][C:29]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[O:30])=[C:6]([CH:21]=1)[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([F:17])([F:19])[F:18])[CH:13]=[CH:12][C:11]=1[Cl:20])=[O:8]

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 17860267HCID 17860267, compound

Product 1

HCID 69067799HCID 69067799, compoundYield 95.1%

Procedure

Using 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]-2-hydroxybenzamide and morpholine-4-carbonyl chloride as the raw materials, the same operation as the Example 71 gave the title compound.

Sources & evidence

ORD record
ord-a7a21532403740af8cbba7214a2b4a95
Source dataset
uspto-grants-2009_12
Patent number
US07626042B2

Reaction notes

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