5-Bromosalicylic acid → HCID 17860173, compound

HRID 1865371Notes

Reaction equation

HRID 1865371 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:15]=1[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:17]=[C:18]([C:21]([F:23])([F:24])[F:22])[CH:19]=[CH:20][C:14]=1[O:13][CH3:12])=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 6006372-Methoxy-5-(trifluoromethyl)aniline

Product 1

HCID 17860173HCID 17860173, compoundYield 71.3%

Procedure

Using 5-bromosalicylic acid and 2-methoxy-5-(trifluoromethyl)aniline as the raw materials, the same operation as the Example 1(1) gave the title compound.

Sources & evidence

ORD record
ord-340d212d1dc54d47b4106a1acdfcc5b3
Source dataset
uspto-grants-2009_12
Patent number
US07626042B2

Reaction notes

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