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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865376Generated: October 25, 2026

4-Morpholinecarbonyl chloride → 5-Bromo-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-[(morpholinocarbonyl)oxy]-benzamide

https://huagongshe.com/reaction/1865376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Morpholinecarbonyl chlorideHCID 84810—
Reactant5-Bromo-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-hydroxybenzamideHCID 17860290—
Product5-Bromo-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-[(morpholinocarbonyl)oxy]-benzamideHCID 6966455493.5%

Reaction Steps

Using 5-bromo-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-hydroxybenzamide and morpholine-4-carbonyl chloride as the raw materials, the same operation as the Example 71 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07626042B2
Source datasetuspto-grants-2009_12
ORD IDord-6636d081322d4c95b129abfa807cf2a1
Source noteuspto-grants-2009_12