4-Morpholinecarbonyl chloride → HCID 69664348, compound

HRID 1865378Notes

Reaction equation

HRID 1865378 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:19])=[C:6]([CH:18]=1)[C:7]([NH:9][C:10]1[CH:15]=[C:14]([Cl:16])[CH:13]=[C:12]([Cl:17])[CH:11]=1)=[O:8].[N:20]1([C:26](Cl)=[O:27])[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:19][C:26]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)=[O:27])=[C:6]([CH:18]=1)[C:7]([NH:9][C:10]1[CH:15]=[C:14]([Cl:16])[CH:13]=[C:12]([Cl:17])[CH:11]=1)=[O:8]

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 2804666HCID 2804666, compound

Product 1

HCID 69664348HCID 69664348, compoundYield 83.2%

Procedure

Using 5-chloro-N-(3,5-dichlorophenyl)-2-hydroxybenzamide and morpholine-4-carbonyl chloride as the raw materials, the same operation as the Example 71 gave the title compound.

Sources & evidence

ORD record
ord-240ef8f4420340a9a7ec3aa74f270784
Source dataset
uspto-grants-2009_12
Patent number
US07626042B2

Reaction notes

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