Benzonitrile, 4-chloro-3-nitro- → HCID 22148777, compound

HRID 1865488Notes

Reaction equation

HRID 1865488 reaction equation
Cl[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[F:13][C:14]1[CH:15]=[C:16]([OH:21])[CH:17]=[C:18]([F:20])[CH:19]=1>>[N+:10]([C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:2]=1[O:21][C:16]1[CH:15]=[C:14]([F:13])[CH:19]=[C:18]([F:20])[CH:17]=1)[C:6]#[N:7])([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 13655Benzonitrile, 4-chloro-3-nitro-HCID 759283,5-Difluorophenol

Product 1

HCID 22148777HCID 22148777, compound

Procedure

In a similar manner, 4-chloro-3-nitrobenzonitrile (4.6 g, 25 mmol) and 3,5-difluorophenol were combined to produce 6.9 g of 3-nitro-4-(3,5-difluorophenoxy)-benzonitrile (26.2), mp 132-136° C.

Sources & evidence

ORD record
ord-db161e4d516e434496a79bfa06b0391c
Source dataset
uspto-grants-2009_12
Patent number
US07626033B2

Reaction notes

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