HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-[3-Chloro-4-(naphthalen-2-ylsulfanyl)-phenyl]-4-iodo-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Iodobenzenesulfonyl chloride | HCID 7399 | — |
| Reactant | 3-Chloro-4-(napthalen-2-ylsulfanyl)-phenylamine | HCID 9861938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-[3-Chloro-4-(naphthalen-2-ylsulfanyl)-phenyl]-4-iodo-benzenesulfonamide | HCID 22148807 | 53% |
Reaction Steps
The title compound was prepared using the method of example 94, starting with 3-chloro-4-(naphthalen-2-ylsulfanyl)-phenylamine (92) (150 mg, 0.53 mmol), pyridine (Aldrich, 0.21 mL, 2.63 mmol) and 4-iodobenzenesulfonyl chloride (Acros, 175 mg, 0.58 mmol) in THF. 153 mg (53%) of 100 was obtained as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626033B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-b244d67894f54d51a3575cf35081460d |
| Source note | uspto-grants-2009_12 |