HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxyquinoline → HCID 23503311, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxyquinoline | HCID 11376 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-1-fluoro-4-nitrobenzene | HCID 67688 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 23503311 | HCID 23503311 | 99.9% |
Reaction Steps
To a solution of 3-hydroxyquinoline (1.00 g) and 3-chloro-4-fluoronitrobenzene (1.21 g) in Acetone (20 ml), was added K2CO3 (2.86 g). The mixture was refluxed for 1 hr. After cooling the reaction mixture was filtered through a short celite pad. The filtrate was concentrated to provide compound 198 (2.07 g, quant.) as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626033B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-8c19031bc0c74bc984e91221ef1e5639 |
| Source note | uspto-grants-2009_12 |