HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonitrile, 4-chloro-3-nitro- → 3-Amino-4-chlorobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonitrile, 4-chloro-3-nitro- | HCID 13655 | — |
| Reactant | Tin tetrachloride dihydrate | HCID 85782573 | — |
| Product | 3-Amino-4-chlorobenzonitrile | HCID 104464 | 98.3% |
Reaction Steps
The title compound was prepared using the method of example 32, starting with 4-chloro-3-nitro-benzonitrile (Fluka, 11.0 g, 60 mmol), tin chloride dihydrate (Aldrich, 67.8 g, 300 mmol). 9.0 g (98%) of crude compound 242 was obtained as a yellowish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626033B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-0fce703e68144e63bc5f0d2a99abe6b9 |
| Source note | uspto-grants-2009_12 |