HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-nitrotoluene → 2-Bromo-5-methylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-nitrotoluene | HCID 79224 | — |
| Reactant | Tin tetrachloride dihydrate | HCID 85782573 | — |
| Product | 2-Bromo-5-methylaniline | HCID 6422065 | 94.4% |
Reaction Steps
The title compound was prepared using the method of example 32, starting with 1-bromo-4-methyl-2-nitro-benzene (Lancaster, 10.1 g, 46.7 mmol), tin chloride dihydrate (Aldrich, 52.8 g, 233 mmol). 8.2 g (94%) of crude compound 244 was obtained as a pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626033B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-86aabc19b65b4559808ee11000ad4ccc |
| Source note | uspto-grants-2009_12 |