HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,6-Dichloro-4-nitro-phenylsulfanyl)-benzothiazole-6-carbonitrile → 2-(4-Amino-2,6-dichloro-phenylsulfanyl)-benzothiazole-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,6-Dichloro-4-nitro-phenylsulfanyl)-benzothiazole-6-carbonitrile | HCID 22148733 | — |
| Reactant | Tin tetrachloride dihydrate | HCID 85782573 | — |
| Product | 2-(4-Amino-2,6-dichloro-phenylsulfanyl)-benzothiazole-6-carbonitrile | HCID 22148799 | 98.2% |
Reaction Steps
The title compound was prepared using the method of example 270, starting with 2-(2,6-dichloro-4-nitro-phenylsulfanyl)-benzothiazole-6-carbonitrile (260) (1.9 g, 4.97 mmol), tin chloride dihydrate (Aldrich, 5.62 g, 24.9 mmol). Compound 272 (1.72 g, 98%) was obtained as a yellowish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626033B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-c629307e5689498daa13b1f09bef15f2 |
| Source note | uspto-grants-2009_12 |