HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,6-Dichloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile → 2-(4-Amino-2,6-dichlorophenylsulfanyl)-benzothiazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,6-Dichloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile | HCID 22148768 | — |
| Reactant | Tin tetrachloride dihydrate | HCID 85782573 | — |
| Product | 2-(4-Amino-2,6-dichlorophenylsulfanyl)-benzothiazole-5-carbonitrile | HCID 22148826 | 80% |
Reaction Steps
The title compound was prepared using the method of example 270, starting with 2-(2,6-dichloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile (262) (1.9 g, 4.97 mmol), tin chloride dihydrate (Aldrich, 5.62 g, 24.9 mmol). Compound 274 (1.40 g, 80%) was obtained as a yellowish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07626033B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-532afee4680d4422813184b5c1edf740 |
| Source note | uspto-grants-2009_12 |