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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865779Generated: October 25, 2026

O-Methylhydroxylamine → 1-(2'-C-methyl-beta-D-ribofuranosyl)-4-methoxylamino-pyrazolo[3,4-d]pyrimidine

https://huagongshe.com/reaction/1865779

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-MethylhydroxylamineHCID 4113—
Reactant1-(2'-C-methyl-beta-D-ribofuranosyl)-4-hydroxylamino-pyrazolo[3,4-d]pyrimidineHCID 10469885—
Product1-(2'-C-methyl-beta-D-ribofuranosyl)-4-methoxylamino-pyrazolo[3,4-d]pyrimidineHCID 10448156—

Reaction Steps

Nucleoside 119 was prepared from the nucleoside 143 (Example 6, step 3) substituting hydroxylamine for methoxylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629320B2
Source datasetuspto-grants-2009_12
ORD IDord-4a5ea004a0e8466fa348813f08c743d3
Source noteuspto-grants-2009_12