HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorotrityl chloride → HNle 2-chlorotrityl resin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorotrityl chloride | HCID 94524 | — |
| Reactant | (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid | HCID 7009636 | — |
| Product | HNle 2-chlorotrityl resin | HCID 131727815 | 141.4% |
Reaction Steps
The resin was prepared using similar methodology to that described in Example 2 step 2.3 from FmocNleOH (4.37 g) and 2-chlorotrityl chloride resin (7.45 g, 0.83 mmol/g, Novabiochem) to yield 7.77 g HNle-2-chlorotrityl resin (loading: 0.50 mmol/g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629318B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-825d9db8764147b397a8dec195698e7f |
| Source note | uspto-grants-2009_12 |