HCID 87661419, compound → HCID 11983220, compound

HRID 1865841Notes

Reaction equation

HRID 1865841 reaction equation
Cl[C:2]1[C:3]([C:22]2[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=2)=[C:4]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[C:5]2[N:6]([C:8]([C:11]([F:14])([F:13])[F:12])=[N:9][N:10]=2)[N:7]=1.[Si]([O:33][K])(C)(C)C>>[Cl:28][C:25]1[CH:26]=[CH:27][C:22]([C:3]2[C:2](=[O:33])[NH:7][N:6]3[C:8]([C:11]([F:13])([F:12])[F:14])=[N:9][N:10]=[C:5]3[C:4]=2[C:15]2[CH:16]=[CH:17][C:18]([Cl:21])=[CH:19][CH:20]=2)=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 87661419HCID 87661419, compoundHCID 178504318HCID 178504318, compound

Product 1

HCID 11983220HCID 11983220, compound

Procedure

The title compound was synthesized by reacting 6-chloro-7,8-bis(4-chlorophenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine with TMSOK using the procedures described above. 1HNMR (DMSO, 400 Hz): 7.48 (2H, d), 7.38-7.7.42 (4H, m), 7.25 (2H, d). 13CNMR (DMSO, 400 Hz) 160.88, 145.91, 137.00, 135.11, 133.90, 132.94, 132.10, 131.07, 129.98, 128.00 127.13, 118.30(q).

Sources & evidence

ORD record
ord-d2b47bfb235f4dddb7f4c57233bf7540
Source dataset
uspto-grants-2009_12
Patent number
US07629342B2

Reaction notes

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