Cyclopentanemethanol → HCID 86616970, compound

HRID 1865886Notes

Reaction equation

HRID 1865886 reaction equation
[CH:1]1([C:4]([OH:24])([CH3:23])[CH2:5][NH:6][C:7]([C:9]2[CH:14]=[N:13][C:12](Br)=[C:11]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)[N:10]=2)=[O:8])[CH2:3][CH2:2]1.[CH:25]1([CH2:30][OH:31])[CH2:29][CH2:28][CH2:27][CH2:26]1>>[CH:1]1([C:4]([OH:24])([CH3:23])[CH2:5][NH:6][C:7]([C:9]2[CH:14]=[N:13][C:12]([O:31][CH2:30][CH:25]3[CH2:29][CH2:28][CH2:27][CH2:26]3)=[C:11]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)[N:10]=2)=[O:8])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 77195CyclopentanemethanolHCID 866169635-Bromo-6-(4-chloro-phenyl)-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amide

Product 1

HCID 86616970HCID 86616970, compound

Procedure

The title compound was prepared in analogy to example 26 starting from 5-bromo-6-(4-chloro-phenyl)-pyrazine-2-carboxylic acid (-2-cyclopropyl-2-hydroxy-propyl)-amide and replacing ethylenglycolmonomethylether by cyclopentylmethanol. MS (ISP) (M+H+)=430.1.

Sources & evidence

ORD record
ord-8fd3c4bfe266453791be117be67030c2
Source dataset
uspto-grants-2009_12
Patent number
US07629346B2

Reaction notes

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