HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanemethanol → 6-(4-Chloro-phenyl)-5-cyclopentylmethoxy-pyrazine-2-carboxylic acid ((1R,2R)-2-hydroxy-cyclohexyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanemethanol | HCID 77195 | — |
| Reactant | 5-bromo-6-(4-chloro-phenyl)-pyrazine-2-carboxylic acid ((1R,2R)-2-hydroxy-cyclohexyl)-amide | HCID 86616972 | — |
| Product | 6-(4-Chloro-phenyl)-5-cyclopentylmethoxy-pyrazine-2-carboxylic acid ((1R,2R)-2-hydroxy-cyclohexyl)-amide | HCID 86616971 | — |
Reaction Steps
The title compound was prepared in analogy to example 26 starting from 5-bromo-6-(4-chloro-phenyl)-pyrazine-2-carboxylic acid ((1R,2R)-2-hydroxy-cyclohexyl)-amide and replacing ethylenglycolmonomethylether by cyclopentylmethanol. MS (ISP) (M+H+)=430.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629346B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-6b087d823dff4ed0b7eaa456b585c71f |
| Source note | uspto-grants-2009_12 |