HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine, 4-(chloroacetyl)- → HCID 59657615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine, 4-(chloroacetyl)- | HCID 74040 | — |
| Reactant | 1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657623 | — |
| Product | HCID 59657615 | HCID 59657615 | — |
Reaction Steps
Following the general procedure V as described hereinabove, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (the preparation of which have been described in example 19) with commercially available 2-chloro-1-morpholin-4-yl-ethanone as electrophile, the title compound was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629353B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-900a0ba4a15a4aeeaaee441ba04c28c6 |
| Source note | uspto-grants-2009_12 |