HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one → 1'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-5-bromo-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one | HCID 53338700 | — |
| Reactant | 1-Benzyl-2-methyl-1H-indole-3-carboxylic acid | HCID 66743481 | — |
| Product | 1'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-5-bromo-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657536 | — |
Reaction Steps
Following the general procedure I as described above, the acylation of 5-bromo-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one with 1-benzyl-2-methyl-1H-indole-3-carboxylic acid (preparation described in example 1), gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629353B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-d8d0f82e295148ea92cf92b0e3e41104 |
| Source note | uspto-grants-2009_12 |