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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865942Generated: November 3, 2026

3,5-Difluorobenzoyl chloride → HCID 59657711, compound

https://huagongshe.com/reaction/1865942

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorobenzoyl chlorideHCID 145600—
Reactant1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657599—
ProductHCID 59657711HCID 59657711—

Reaction Steps

Following the general procedure VII as described above, the acylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 16) with commercially available 3,5-difluorobenzoyl chloride gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-2ae9bf44d0644accaa1b2a05dbaecee8
Source noteuspto-grants-2009_12