Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865954Generated: November 2, 2026

2-Chloro-1-(3-fluorophenyl)ethan-1-one → HCID 59657660, compound

https://huagongshe.com/reaction/1865954

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-(3-fluorophenyl)ethan-1-oneHCID 22248838—
Reactant1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657623—
ProductHCID 59657660HCID 59657660—

Reaction Steps

Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 19) with commercially available 2-chloro-1-(3-fluoro-phenyl)-ethanone gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-57964c5052a94edea7e499f4e3c204ad
Source noteuspto-grants-2009_12