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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865960Generated: November 3, 2026

3-Fluorobenzyl chloride → HCID 59657609, compound

https://huagongshe.com/reaction/1865960

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorobenzyl chlorideHCID 9974—
Reactant5-bromo-1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657619—
ProductHCID 59657609HCID 59657609—

Reaction Steps

Following the general procedure III as described above, the alkylation of 5-bromo-1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one with commercially available 3-fluorobenzyl chloride gave the title compound. ES-MS m/e (%): 567.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-6c06123f816545c6b36e8b3e1a16a4e9
Source noteuspto-grants-2009_12