HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Phenylphenyl)boronic acid → 1'-[(1-Biphenyl-3-yl-6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Phenylphenyl)boronic acid | HCID 2734315 | — |
| Reactant | 1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657599 | — |
| Product | 1'-[(1-Biphenyl-3-yl-6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657717 | — |
Reaction Steps
Following the general procedure VI as described above, the arylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 16) with commercially available 3-biphenylboronic acid gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629353B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-d475c2ef5ef9426a911782a8e53f2453 |
| Source note | uspto-grants-2009_12 |