Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865983Generated: November 1, 2026

4-Benzyl-2-(chloromethyl)morpholine → HCID 59657718, compound

https://huagongshe.com/reaction/1865983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyl-2-(chloromethyl)morpholineHCID 2801562—
Reactant1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657623—
ProductHCID 59657718HCID 59657718—

Reaction Steps

Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 19 above) with commercially available 4-benzyl-2-(chloromethyl)morpholine gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-9d9e906c71754e17adf5b3b36bc26d54
Source noteuspto-grants-2009_12