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HRID1865997

反应详情

EQUATION

反应方程式

HRID 1865997 的结构方程式

REACTANTS

反应物

2
结构：COCC1(CBr)CC1
HCID17937352

1-(Bromomethyl)-1-(methoxymethyl)cyclopropane

C6H11BrO

结构：O=C1OC2(CCN(C(=O)c3c[nH]c4cc(Cl)ccc34)CC2)c2ccc(F)cc21
HCID59657623

未命名化合物

PRODUCTS

生成物

1
结构：COCC1(Cn2cc(C(=O)N3CCC4(CC3)OC(=O)c3cc(F)ccc34)c3ccc(Cl)cc32)CC1
HCID57978141

未命名化合物

PROCEDURE

实验过程

Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 19) with 1-bromomethyl-1-methoxymethyl-cyclopropane (described in WO 2001032633) gave the title compound.