HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Bromoethyl)oxane → HCID 59657647, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Bromoethyl)oxane | HCID 22637012 | — |
| Reactant | 1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657599 | — |
| Product | HCID 59657647 | HCID 59657647 | — |
Reaction Steps
Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 16) with 4-(2-bromo-ethyl)-tetrahydro-pyran (described in US 2004220214) gave the title compound. ES-MS m/e (%): 493.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629353B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-47d58755d8fe4cdf8895f9fa542370cd |
| Source note | uspto-grants-2009_12 |