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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1866003Generated: November 1, 2026

2-Chloro-1-piperidine-1-yl-ethanone → HCID 59657621, compound

https://huagongshe.com/reaction/1866003

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-piperidine-1-yl-ethanoneHCID 222312—
Reactant(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanoneHCID 15951937—
ProductHCID 59657621HCID 59657621—

Reaction Steps

Following the general procedure V as described hereinabove, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidine] (the preparation of which have been described in example 69) with commercially available 2-chloro-1-piperidin-1-yl-ethanone as electrophile, the title compound was obtained as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-089176009fde4b20a05f0fe690a09c7a
Source noteuspto-grants-2009_12