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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1866004Generated: November 1, 2026

Morpholine, 4-(chloroacetyl)- → HCID 59657606, compound

https://huagongshe.com/reaction/1866004

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholine, 4-(chloroacetyl)-HCID 74040—
Reactant(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanoneHCID 15951937—
ProductHCID 59657606HCID 59657606—

Reaction Steps

Following the general procedure V as described hereinabove, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidine] (the preparation of which have been described in example 69) with commercially available 2-Chloro-1-morpholin-4-yl-ethanone as electrophile, the title compound was obtained as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-6c97942a19174f4eab9d1dc3251993be
Source noteuspto-grants-2009_12