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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1866026Generated: November 4, 2026

(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone → HCID 59657701, compound

https://huagongshe.com/reaction/1866026

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanoneHCID 15951937—
ReactantHCID 22662916HCID 22662916—
ProductHCID 59657701HCID 59657701—

Reaction Steps

Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidine] (prepared according to example 69) with methanesulfonic acid pyrrolidin-3-ylmethyl ester (described in WO 9742189) gave the title compound. ES-MS m/e (%): 450.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629353B2
Source datasetuspto-grants-2009_12
ORD IDord-98bbd551c3d643a5b80fe36b7705bce6
Source noteuspto-grants-2009_12