5-bromo-2-chloro-N-phenylpyrimidin-4-amine → 4-Anilino-5-bromo-2-(4-{N-[2-hydroxy-3-(N,N-dimethylamino)propyl]-N-methylamino}anilino)pyrimidine
Reaction equation
[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9][c:10]([Cl:15])[n:11][cH:12][c:13]1[Br:14].[OH:16][CH:17]([CH2:18][N:19]([CH3:20])[c:21]1[cH:22][cH:23][c:24]([NH2:25])[cH:26][cH:27]1)[CH2:28][N:29]([CH3:30])[CH3:31]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9][c:10]([NH:25][c:24]2[cH:23][cH:22][c:21]([N:19]([CH2:18][CH:17]([OH:16])[CH2:28][N:29]([CH3:30])[CH3:31])[CH3:20])[cH:27][cH:26]2)[n:11][cH:12][c:13]1[Br:14]Participants
3
Sources & evidence
- ORD record
- ord-b9bb50c9253045848687b26aaad48099
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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