1-(4-Fluorophenyl)piperazine → HCID 11698311, compound

Participants

Reaction Steps

Treat 5-formyl-3-phenylsulfanyl-1H-indole-2-carboxylic acid amide 13 (m=0, R3=Ph) (80 mg, 0.27 mmol) with 1-(4-fluorophenyl)piperazine (90 mg, 0.50 mmol) as described in General Procedure X to afford Iaa (69.0 mg, 55.6%) as an ivory colored solid, tlc Rf=0.4 (10% MeOH/CH2Cl2-0.20% Et3N), m/z obs=461 (M+1).

Provenance & Evidence