HuagongsheHuagongshe Chemistry Print Report · For research reference only
Alanine methyl ester hydrochloride → (S)-2-[(7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Alanine methyl ester hydrochloride | HCID 2733257 | — |
| Reactant | 7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid | HCID 18698130 | — |
| Product | (S)-2-[(7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-propionic acid methyl ester | HCID 86595454 | — |
Reaction Steps
7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid, 0.33 g, was coupled with L-Alanine methyl ester hydrochloride, 0.150 g, analogously to Example A-1 a). 0.264 G of white solid were obtained: MS-(+)-ion, M+1=415. amu.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629357B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-3c3565baffd54d35b71f8e9f45e447f1 |
| Source note | uspto-grants-2009_12 |