3-Quinuclidinol, (-)- → HCID 68824417, compound

HRID 1866782Notes

Reaction equation

HRID 1866782 reaction equation
[C:1]1([N:7]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C@@H:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:10][C@@H:9]2[O:24][CH3:25])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:32]12CC[CH:35]([CH2:36][CH2:37]1)[C@@H:34](O)[CH2:33]2>>[C:26]1([N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C@@H:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([O:21][C@@H:22]3[CH:35]4[CH2:36][CH2:37][N:32]([CH2:33][CH2:34]4)[CH2:23]3)=[O:20])[CH2:10][C@@H:9]2[O:24][CH3:25])[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 914043-Quinuclidinol, (-)-HCID 68822024HCID 68822024, compound

Product 1

HCID 68824417HCID 68824417, compound

Procedure

esterifying the ethyl 6-((3S,4R)-4-(diphenylamino)-3-methoxypiperidin-1-yl)hexanoate with (R)-quinuclidine-3-ol to yield (R)-quinuclidine-3-yl 6-((3S,4R)-4-(diphenylamino)-3-methoxypiperidin-1-yl)hexanoate

Sources & evidence

ORD record
ord-9918504067d74df6b920ba5f7d309751
Source dataset
uspto-grants-2009_12
Patent number
US07629466B2

Reaction notes

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