反应详情

To a solution of [1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-carbamic acid benzyl ester (1.5 g, 4.67 mmol) in methanol (25 mL) was added 10% palladium on carbon (0.16 g). The mixture was shaken in a hydrogenation apparatus at rt under a hydrogen atmosphere (10 psi) for 8 h. Filtration followed by evaporation to dryness under reduced pressure yielded the crude product 1-(4-phenyl-1H-imidazol-2-yl)-ethylamine.

1. filtrationFiltration
2. customfollowed by evaporation to dryness under reduced pressure