Hydrochloric Acid → HCID 22050202, compound

Participants

Reaction Steps

The product of Step 1, (2.9 g, 5.3 mmol) was dissolved in tetrahydrofuran (75 mL) and 6N HCl (10 mL). The reaction mixture was heated at 60 C for 18 h and was concentrated in vacuo to give the final product (1.89 g, 75%). 1H NMR (400 MHz, CD3OD) δ 7.64 (q, J=8.4 and 15.2 Hz, 1H), 7.56 (m, 2H), 7.46 (m, 1H), 7.05 (m, 2H), 6.69 (s, 1H), 5.37 (s, 2H), 2.10 (s, 3H) ppm. 19F NMR (400 MHz, CD3OD) δ −111.37 (1F), −115.86 (1F), −123.16 ppm. ES-HRMS m/z 440.0334 (M+H calcd for C19H15BrF3N2O2 requires 440.0295).

Provenance & Evidence