1-(2-Chloroethyl)pyrrolidine → HCID 67080869, compound

HRID 1867360Notes

Reaction equation

HRID 1867360 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][C:12](=[O:15])[NH:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[CH2:17][CH2:18][N:19]1[CH2:23][CH2:22][CH2:21][CH2:20]1>>[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][C:12](=[O:15])[N:11]([CH2:17][CH2:18][N:19]2[CH2:23][CH2:22][CH2:21][CH2:20]2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 816691-(2-Chloroethyl)pyrrolidineHCID 226177365-Oxo-(1,4)diazepane-1-carboxylic acid tert-butyl ester

Product 1

HCID 67080869HCID 67080869, compound

Procedure

In analogy to the procedure described in intermediate 4A, 5-oxo-[1,4]diazepane-1-carboxylic acid tert-butyl ester and 1-(2-chloro-ethyl)-pyrrolidine gave the title compound as light yellow solid. MS: 312.0 (MH+).

Sources & evidence

ORD record
ord-6dec5e5f549b416fb850d300fbc00e56
Source dataset
uspto-grants-2009_12
Patent number
US07632829B2

Reaction notes

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