HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cinnamic Acid → 1-[(e)-(3-Phenyl-acryloyl)]-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cinnamic Acid | HCID 444539 | — |
| Reactant | 4-(3-Piperidin-1-yl-propyl)-[1,4]diazepan-5-one dihydrochloride | HCID 67080747 | — |
| Product | 1-[(e)-(3-Phenyl-acryloyl)]-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one | HCID 68432109 | — |
Reaction Steps
In analogy to the procedure described in example 11A, 4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one-dihydrochloride (intermediate 4B) and (E)-cinnamic acid gave the title compound as off-white solid. MS: 370.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632829B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-edd0a46ba3b84c42966fd2d2171248f1 |
| Source note | uspto-grants-2009_12 |