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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 186744Generated: October 25, 2026

5-chloro-2-(trifluoromethyl)-1,8-Naphthyridine → 6,2'-Difluoro-5'-(7-trifluoromethyl[1,8]naphthyridin-4-yl)biphenyl-3-carbonitrile

https://huagongshe.com/reaction/186744

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-chloro-2-(trifluoromethyl)-1,8-NaphthyridineHCID 22285276—
Reactant6,2'-Difluoro-5'-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)biphenyl-3-carbonitrileHCID 22285301—
Product6,2'-Difluoro-5'-(7-trifluoromethyl[1,8]naphthyridin-4-yl)biphenyl-3-carbonitrileHCID 10158525—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6447eca117234ac38f1a3d47ab58fce1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)