5-Bromo-2,1,3-benzoxadiazole → HCID 86604698, compound

HRID 1867518Notes

Reaction equation

HRID 1867518 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]2[C:6]([CH:10]=1)=[N:7][O:8][N:9]=2.C(OC(=O)[N:17]([C:21]1[CH:26]=[CH:25][C:24](Br)=[C:23]([O:28][CH3:29])[CH:22]=1)[CH2:18][CH2:19][F:20])(C)(C)C>>[N:9]1[O:8][N:7]=[C:6]2[CH:10]=[C:2]([C:24]3[CH:25]=[CH:26][C:21]([NH:17][CH2:18][CH2:19][F:20])=[CH:22][C:23]=3[O:28][CH3:29])[CH:3]=[CH:4][C:5]=12

Participants

3

Reactant 2

HCID 27762985-Bromo-2,1,3-benzoxadiazoleHCID 86604699HCID 86604699, compound

Product 1

HCID 86604698HCID 86604698, compound

Procedure

The starting compound is obtained according to the procedure described in Example 7 from 5-bromo-benzo[1,2,5]oxadiazole and (4-bromo-3-methoxy-phenyl)-(2-fluoro-ethyl)-carbamic acid tert-butyl ester, as a yellow glass. MS(ES+): 410 (M+23).

Workup

  1. customThe starting compound is obtained

Sources & evidence

ORD record
ord-12448b13795247ea8d8609fcddc00345
Source dataset
uspto-grants-2009_12
Patent number
US07632851B2

Reaction notes

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