HCID 11557535, compound → HCID 11593583, compound

HRID 1867570Notes

Reaction equation

HRID 1867570 reaction equation
Cl[C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][N:6]2[CH2:11][C:12]([NH2:14])=[O:13].[F:15]C(F)(F)C1C=CC=C2C=1C=CN2CC(N)=O>>[F:15][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][N:6]2[CH2:11][C:12]([NH2:14])=[O:13]

Participants

3

Reactant 2

HCID 11557535HCID 11557535, compoundHCID 11665905HCID 11665905, compound

Product 1

HCID 11593583HCID 11593583, compound

Procedure

2-(4-chloro-1H-indol-1-yl)acetamide 2 (MS (LC-MS, MH+): 209/211)) and 2-[4-(trifluoromethyl)-1H-indol-1-yl]acetamide 2a can be synthesized according to the same method.

Sources & evidence

ORD record
ord-07e68bb18dc749a3983243c061eb4a2d
Source dataset
uspto-grants-2009_12
Patent number
US07632856B2

Reaction notes

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