Trifluoroacetic acid → HCID 57979573, compound

Participants

Reaction Steps

Trifluoroacetic acid (0.600 mL) was added to a solution tert-butyl 4-[4-(4-methylphenyl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]piperidine-1-carboxylate (178.4 mg, 0.50 mmol) in dichloromethane (3 mL). After 16 h, the reaction was concentrated and purified by reverse phase HPLC (C-18 column, 95% water/acetonitrile→5% water/acetonitrile with 0.1% trifluoroacetic acid) to give the title product. MS 258.1 (M+1).

Provenance & Evidence