Sodium ethoxide → HCID 18321616, compound

Participants

Reaction Steps

Sodium ethoxide (0.1301 mL, 1.66 mmol, 21% wt.) was added to a solution of methyl N-{[(1-benzylpiperidin-4-yl)amino]carbonyl}phenylalaninate (546 mg, 1.38 mmol) in ethanol (715 mL) at 0° C. and then warmed to ambient temperature. The reaction was concentrated and partitioned between ethyl acetate and water. The organic layer was washed with brine, dried over sodium sulfate, filtered, and concentrated to give the title compound (490 mg). MS 364.2 (M+1)

Provenance & Evidence